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100 day countdown

The 100 day countdown is an important factor for stem cell transplant patients. Firstly, 100 days is when a bone marrow aspiration will take place to determine the early success of the transplant. Secondly, it is a marker determining Graft versus Host Disease (GvHD). Acute - Graft versus Host Disease occurs within the first 100 days Chronic - Graft versus Host Disease occurs after the first 100 days It is difficult to say who will develop GvHD after a transplant, but somewhere between one and four out of every five people (20 to 80 per cent) having a donor transplant will develop some degree of GvHD. Some people have a very mild form which doesn’t last long. For others, GvHD can be severe.
Acute GvHD: Acute GvHD often starts with a rash on the palms of your hands and soles of your feet. Or you may have a rash on your face. The rash may be itchy. Acute GvHD may also affect your mouth, gut (digestive system) and liver, as well as your skin. This can cause diarrhoea, nausea, loss of appetite, and yellowing of the skin (jaundice). Chronic GvHD Chronic GvHD can follow acute GvHD. It can appear several months after your transplant, even if you’ve not had the acute form. But you are more likely to get chronic GvHD if you have had acute GvHD. Like acute GvHD it may affect your skin, gut, liver or mouth. But it can also affect other parts of your body, such as your eyes, lungs and joints. Chronic GvHD may be mild or severe, and for some people can go on for several months or even years. For more information, click on the icon below